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sted microscope platform stedycon  (abberior instruments)

 
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    Structured Review

    abberior instruments sted microscope platform stedycon
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Sted Microscope Platform Stedycon, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sted microscope platform stedycon/product/abberior instruments
    Average 90 stars, based on 1 article reviews
    sted microscope platform stedycon - by Bioz Stars, 2026-05
    90/100 stars

    Images

    1) Product Images from "Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells"

    Article Title: Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells

    Journal: International Journal of Molecular Sciences

    doi: 10.3390/ijms252413365

    STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Figure Legend Snippet: STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).

    Techniques Used: Control, Labeling, Concentration Assay, Staining



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    sted microscope platform stedycon  (abberior instruments)
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    abberior instruments sted microscope platform stedycon
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Sted Microscope Platform Stedycon, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sted microscope platform stedycon/product/abberior instruments
    Average 90 stars, based on 1 article reviews
    sted microscope platform stedycon - by Bioz Stars, 2026-05
    90/100 stars
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    stedycon microscope platform  (abberior instruments)
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    abberior instruments stedycon microscope platform
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
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    https://www.bioz.com/result/stedycon microscope platform/product/abberior instruments
    Average 90 stars, based on 1 article reviews
    stedycon microscope platform - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    stedycon sted microscope platform  (Carl Zeiss)
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    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
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    https://www.bioz.com/result/stedycon sted microscope platform/product/Carl Zeiss
    Average 90 stars, based on 1 article reviews
    stedycon sted microscope platform - by Bioz Stars, 2026-05
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    		  Buy from Supplier
    stedycon sted microscope platform  (abberior instruments)
    90
    abberior instruments stedycon sted microscope platform
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Stedycon Sted Microscope Platform, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/stedycon sted microscope platform/product/abberior instruments
    Average 90 stars, based on 1 article reviews
    stedycon sted microscope platform - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).

    Journal: International Journal of Molecular Sciences

    Article Title: Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells

    doi: 10.3390/ijms252413365

    Figure Lengend Snippet: STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).

    Article Snippet: STED imaging was performed on a STED microscope platform (STEDYCON, Abberior Instruments GmbH, Göttingen, Germany) equipped with an upright Zeiss Axioimager Z.2 microscope (Zeiss Microscopy GmbH, Oberkochen, Germany) and a pulsed STED laser (Abberior Instruments GmbH) with a depletion wavelength of 775 nm working at a repetition rate of 40 MHz, a pulse duration of 1 ns, using STEDYCON SmartControl software version 9.

    Techniques: Control, Labeling, Concentration Assay, Staining